USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: GLRX3_HUMAN USC-OGP 2-DE database:  GLRX3_HUMAN GLRX3_HUMAN General information about the entry View entry in simple text format Entry name GLRX3_HUMAN Primary accession number Q9P1B0 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Glutaredoxin-3; AltName: Full=PKC-interacting cousin of thioredoxin {ECO:0000303|PubMed:10636891}; Short=PICOT {ECO:0000303|PubMed:10636891}; AltName: Full=PKC-theta-interacting protein; Short=PKCq-interacting protein; AltName: Full=Thioredoxin-like protein 2;. Gene name Name=GLRX3 Synonyms=PICOT {ECO:0000303|PubMed:10636891}, TXNL2 ORFNames=HUSSY-22 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0427: pI=5.23; Mw=40510 Cross-references UniProtKB/Swiss-Prot O76003; GLRX3_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name GLRX3_HUMAN Primary accession number O76003 Secondary accession number(s) B3KMP7 B3KMQ5 D3DRG2 Q5JV01 Q96CE0 Q9P1B0 Q9P1B1 Sequence was last modified on  September 26, 2003 (version 2) Annotations were last modified on  March 15, 2017 (version 170) Name and origin of the protein Description RecName: Full=Glutaredoxin-3; AltName: Full=PKC-interacting cousin of thioredoxin {ECO:0000303|PubMed:10636891}; Short=PICOT {ECO:0000303|PubMed:10636891}; AltName: Full=PKC-theta-interacting protein; Short=PKCq-interacting protein; AltName: Full=Thioredoxin-like protein 2; Gene name Name=GLRX3 Synonyms=PICOT {ECO:0000303|PubMed:10636891}, TXNL2 ORFNames=HUSSY-22 Encoded on Name=GLRX3; Synonyms=PICOT {ECO:0000303|PubMed:10636891}, TXNL2; ORFNames=HUSSY-22 Keywords 3D-structure; Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Iron; Iron-sulfur; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF118649; AAF28841.1; -; mRNA EMBL AF118652; AAF28844.1; -; mRNA EMBL AJ010841; CAA09375.1; -; mRNA EMBL AK022131; BAG51067.1; -; mRNA EMBL AK021926; BAG51059.1; -; mRNA EMBL AL139123; CAC40691.1; -; Genomic_DNA EMBL CH471066; EAW49152.1; -; Genomic_DNA EMBL CH471066; EAW49154.1; -; Genomic_DNA EMBL CH471066; EAW49155.1; -; Genomic_DNA EMBL BC005289; AAH05289.1; -; mRNA EMBL BC014372; AAH14372.2; -; mRNA CCDS CCDS7661.1; -; . RefSeq NP_001186797.1; NM_001199868.1; . RefSeq NP_006532.2; NM_006541.4; . UniGene Hs.42644; -; . PDB 2DIY; NMR; -; A=1-117 PDB 2WZ9; X-ray; 1.55 A; A=1-125 PDB 2YAN; X-ray; 1.90 A; A/B=232-334 PDB 3ZYW; X-ray; 1.84 A; A/B=130-232 PDBsum 2DIY; -; . PDBsum 2WZ9; -; . PDBsum 2YAN; -; . PDBsum 3ZYW; -; . ProteinModelPortal O76003; -; . SMR O76003; -; . BioGrid 115793; 89; . DIP DIP-31306N; -; . IntAct O76003; 94; . MINT MINT-5002296; -; . STRING 9606.ENSP00000330836; -; . iPTMnet O76003; -; . PhosphoSitePlus O76003; -; . BioMuta GLRX3; -; . REPRODUCTION-2DPAGE IPI00008552; -; . EPD O76003; -; . MaxQB O76003; -; . PaxDb O76003; -; . PeptideAtlas O76003; -; . PRIDE O76003; -; . Ensembl ENST00000331244; ENSP00000330836; ENSG00000108010; . Ensembl ENST00000368644; ENSP00000357633; ENSG00000108010; . Ensembl ENST00000481034; ENSP00000435445; ENSG00000108010; . GeneID 10539; -; . KEGG hsa:10539; -; . UCSC uc001lkm.3; human; . CTD 10539; -; . DisGeNET 10539; -; . GeneCards GLRX3; -; . HGNC HGNC:15987; GLRX3; . HPA HPA028941; -; . MIM 612754; gene; . neXtProt NX_O76003; -; . OpenTargets ENSG00000108010; -; . PharmGKB PA162389829; -; . eggNOG KOG0911; Eukaryota; . eggNOG COG0278; LUCA; . GeneTree ENSGT00550000075030; -; . HOVERGEN HBG054719; -; . InParanoid O76003; -; . OMA WAPQCTQ; -; . OrthoDB EOG091G0YN0; -; . PhylomeDB O76003; -; . TreeFam TF314151; -; . ChiTaRS GLRX3; human; . EvolutionaryTrace O76003; -; . GeneWiki GLRX3; -; . GenomeRNAi 10539; -; . PMAP-CutDB O76003; -; . PRO PR:O76003; -; . Proteomes UP000005640; Chromosome 10; . Bgee ENSG00000108010; -; . CleanEx HS_GLRX3; -; . ExpressionAtlas O76003; baseline and differential; . Genevisible O76003; HS; . GO GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell; . GO GO:0030425; C:dendrite; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IEA:Ensembl; . GO GO:0030018; C:Z disc; IEA:UniProtKB-SubCell; . GO GO:0009055; F:electron carrier activity; IEA:InterPro; . GO GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW; . GO GO:0046872; F:metal ion binding; IEA:UniProtKB-KW; . GO GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0045454; P:cell redox homeostasis; IEA:InterPro; . GO GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:UniProtKB; . GO GO:0002026; P:regulation of the force of heart contraction; ISS:UniProtKB; . CDD cd03028; GRX_PICOT_like; 2; . Gene3D 3.40.30.10; -; 3; . InterPro IPR002109; Glutaredoxin; . InterPro IPR033658; GRX_PICOT-like; . InterPro IPR004480; Monothiol_GRX-rel; . InterPro IPR012336; Thioredoxin-like_fold; . InterPro IPR013766; Thioredoxin_domain; . PANTHER PTHR10293; PTHR10293; 1; . Pfam PF00462; Glutaredoxin; 2; . Pfam PF00085; Thioredoxin; 1; . SUPFAM SSF52833; SSF52833; 3; . TIGRFAMs TIGR00365; TIGR00365; 1; . PROSITE PS51354; GLUTAREDOXIN_2; 2; . PROSITE PS51352; THIOREDOXIN_2; 1; .

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